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Estimate the Maximum AUC

Source: R/max_auc.R
max_auc.Rd

Estimate the maximum AUC of a polygenic risk score based on the population prevalence of a disease k and the proportion of variability explained by the PRS pve.

Usage

max_auc(k, pve, n.bins = 100)

Arguments

k

(numeric; range 0-1) Population prevalence of the disease of interest

pve

(numeric; range 0-1) Proportion of variability explained by the PRS

n.bins

(integer) Number of bins for estimating the AUC (default = 100)

Value

A numeric value for the maximum AUC

Examples

max_auc(k = 0.13, pve = 0.26)
#> [1] 0.8882527