2025
1. Vakilpour A, Levin MG, Anyanwu EC, Denduluri S, Ravindra K, Boakye E, Duqueney E, Cutts JA, Giffin LC, Weber IK, Lee JN, Adusumalli S, Lopez-Mattei J, Chittams J, Jones DB, Weiss K, Hartwell C, Bolooki M, Bourque JM, Scherrer-Crosbie M. Referral patterns and clinical outcomes in patients with severe aortic stenosis: A multicenter cohort study. American Heart Journal. 2025;290:347-358. doi:10.1016/j.ahj.2025.07.014
2. Shah T, Coratti S, Farraday D, Norton L, Rareshide C, Zhu J, Levin MG, Park S-H, Damrauer SM, Giri JS, Chokshi NP, Jackson BM, Patel MS, Fanaroff AC. Effect of Opt-in versus Opt-out Framing on Trial Recruitment: A Study Within A Trial of the GAMEPAD Randomized Trial. American Heart Journal.:107285. doi:10.1016/j.ahj.2025.107285
3. Lee KM, Alba PR, Biagetti GM, Gao A, Yin M, Danilov PN, DiNatale T, Perez C, Hartmann K, Shakt GE, Judy RL, Bellomo TR, Pridgen KM, Tsao PS, Balasundaram N, Levin MG, Damrauer SM, Lynch JA. Using natural language processing to extract carotid stenosis severity from clinical notes to create a nationwide Veteran cohort. JVS-Vascular Insights.:100302. doi:10.1016/j.jvsvi.2025.100302
4. Vujkovic M, Kaplan DE, Ghouse J, Loza B-L, Brancale J, Lewis A, Zhang DY, Levin MG, Veatch OJ, Johnson JP, Schneider CV, Verma A, Wangensteen KJ, Scorletti E, Gill D, Konkwo C, Garofalo AM, Guare LA, Schwantes-An T-W, Abreu MV, Gellert-Kristensen H, Pedersen OB, Erikstrup C, Bundgaard JS, Sorensen E, Ostrowski SR, Bundgaard H, Lee KM, Shaked A, Olthoff KM, Hoteit MA, Speliotes EK, Chen Y, Oliveri A, Yin L, Valenti LV, Malvestiti F, Marchelli D, Miano L, Anstee QM, Daly AK, Cordell HJ, Darlay R, Verweij N, Hindy G, Locke A, Matsuura K, Asrani SK, Testa G, Trotter JF, Lotta LA, Jones MB, Dochtermann DR, Norden-Krichmar TM, Teerlink CC, Devineni P, Pyarajan S, Rader DJ, Tanaka Y, Voight BF, Vilarinho S, Bastarache LA, Stender S, Tsao PS, Biobank PM, Consortium DG, Biobank B, Initiative MG, Center RG, Biobank I, Program AOUR, Biobank M, Consortium L, Program VMV, Morgan TR, Lynch JA, Chang K-M. Germline Variants Influence Chronic Liver Disease Progression through Distinct Pathways. doi:10.1101/2025.09.16.25335186
5. Yuan S, Khodursky S, Geng J, Sharma P, Spin JM, Tsao PS, Levin MG, Damrauer SM. Circulating Protein Mediators Linking Genetically Predicted Smoking to Abdominal Aortic Aneurysm: A Genomic-Proteomic Analysis. Arteriosclerosis, Thrombosis, and Vascular Biology. 2025;45(9):1683-1692. doi:10.1161/ATVBAHA.125.323057
6. Ha KT, Hartmann K, Judy R, Levin M, Damrauer SM, Thom CS. Genetically determined platelet traits impact stroke risk through multiple mechanisms and cell types. doi:10.1101/2025.08.01.25332822
7. Munsch G, Thibord F, Bezerra OC, Brody JA, Hylckama Vlieg A van, Gourhant L, Chen M-H, Samaria F, Germain M, Caro I, Suchon P, Olaso R, Wiggins KL, Saut N, Besse C, Goumidi L, Bacq D, Harrington LB, Boland A, Trégouët D-A, O’Donnell C, Bis JC, Wiggins KL, Psaty BM, Marioni R, Yang Q, Wei P, Conomos MP, McKnight B, Wild PS, Asselbergs FW, Jukema JW, Harst P van der, Mook-Kanamori D, Vlieg A van H, Rosendaal FR, Li R, Dehghan A, Elliot P, Gill D, Kavousi M, Peyser PA, Bielak LF, Jhun M-A, Brody JA, Smith NL, Reiner AP, Homuth G, Völker U, Nicholas J, Raffield LM, Maat MPM de, Leebeek FWG, Felix SB, Pankratz N, Yanek LR, Desch KC, Cox SR, Damrauer SM, Mangino M, Chasman D, Koenig W, Campbell H, Morange P, Heath AS, Morrison AC, Vries PS de, Brown MR, Hahn JM, Bressler J, Davies G, Huffman JE, Wilson JF, Richmond A, Hayward C, Johnson A, Thibord F, Liu M, Ward-Caviness C, Strachan DP, Chen M-H, Peters A, Mueller M, Tang W, Trompet S, Kleber ME, Taylor HA, Rotter JI, Yao J, Guo X, Temprano G, Sabater-Lleal M, Thibord F, Klarin D, Brody JA, Chen M-H, Levin M, Chasman D, et al. Molecular Determinants of Thrombosis Recurrence Risk Across Venous Thromboembolism Subtypes. Blood. doi:10.1182/blood.2024027879
8. Seagle HM, Akerele AT, DeCorte JA, Hellwege JN, Breeyear JH, Kim J, Levin MG, Khodursky S, Bress A, Lee KM, Meiler J, Gill D, Lee JS, Heberer K, Miller DR, Reaven PD, Chang K-M, Lynch JA, Khankari NK, Shuey MM, Edwards TL, Vujkovic M. Genomics-informed drug-repurposing strategy identifies two therapeutic targets for preventing liver disease associated with metabolic dysfunction. The American Journal of Human Genetics. 2025;112(8):1778-1791. doi:10.1016/j.ajhg.2025.06.014
9. Bowles AE, Lynch JA, Bermudez F, Shakt GE, DiNatale T, Pridgen KM, Judy RL, Levin MG, Hartmann K, Damrauer SM, Alba PR. Automated detection of bicuspid aortic valve from echocardiographic reports using natural language processing: A large-scale Veterans Affairs study. doi:10.1101/2025.06.30.25330573
10. Cho SMJ, Levin M, Chen R, Samarakoon R, Judy R, Hartmann K, Postupaka D, Viscosi V, Farber-Eger E, Fahed AC, Honigberg MC, Patel CJ, Hornsby W, Wells QS, Damrauer SM, Do R, Natarajan P. AHA PREVENT Equations and Cardiovascular Disease Risk in Diverse Health Care Populations. Journal of the American College of Cardiology. 2025;86(3):181-192. doi:10.1016/j.jacc.2025.04.066.
11. Woerner J, Westbrook TM, Joo J, Shivakumar M, Venkatesh R, Cherlin T, Jung S-H, Jeong S, Maseda D, McKeague M, Shwetank, Ionita M, Wagenaar J, Abramowitz SA, Verma A, Zhao B, Lee S, Damrauer S, Levin MG, Heo SC, Cappola TP, Rader DJ, Day S, Deo R, Gelfand JM, Ramessur R, Guerraty MA, Setia-Verma S, Pasaniuc B, Ritchie MD, Apostolidis SA, Greenplate AR, Wherry EJ, Biobank PM, Nam Y, Kim D. Large-scale evaluation of proteomic and polygenic risk scores reveals complementary contributions to incident disease prediction. doi:10.1101/2025.07.10.25331242
12. Yuan S, Chen J, Ruan X, Li Y, Abramowitz SA, Wang L, Jiang F, Xiong Y, Levin MG, Voight BF, Gill D, Burgess S, Åkesson A, Michaëlsson K, Li X, Damrauer SM, Larsson SC. Cross-population GWAS and proteomics improve risk prediction and reveal mechanisms in atrial fibrillation. Nature Communications. 2025;16(1):6426. doi:10.1038/s41467-025-61720-2
13. Abramowitz SA, Hoffman-Andrews L, Zhang D, Judy R, Cappola TP, Day SM, Reza N, Owens AT, Damrauer SM, Levin MG. Polygenic Background and Penetrance of Pathogenic Variants in Hypertrophic and Dilated Cardiomyopathies. doi:10.1101/2025.06.20.25329138
14. Adkar SS, Lynch J, Choi RB, Roychowdhury T, Judy RL, Paruchuri K, Go D-C, Bamezai S, Cabot J, Sorondo S, Levin MG, Milewicz DM, Willer CJ, Natarajan P, Pyarajan S, Chang K-M, Damrauer S, Tsao P, Skirboll S, Leeper NJ, Klarin D. Dissecting the Genetic Architecture of Intracranial Aneurysms. Circulation Genomic and Precision Medicine. 2025;18(3):e004626. doi:10.1161/CIRCGEN.123.004626
15. DePaolo J, Bornstein MR, Judy R, Abramowitz S, Verma SS, Levin MG, Biobank PM, Arany Z, Damrauer SM. Titin-Truncating variants predispose to dilated cardiomyopathy in populations genetically similar to african and european reference populations. PLoS genetics. 2025;21(6):e1011727. doi:10.1371/journal.pgen.1011727
16. Fessehaie NA, Bediako H, Kallan MJ, Levin M, Adusumalli S, Bravo P, Pieretti J, Scherrer-Crosbie M, Ferrari VA, Denduluri S, Anyanwu E, Julien H, Eberly LA. Utilization rates and determinants of PYP and CMR among patients with unexplained left ventricular hypertrophy on echocardiography. International Journal of Cardiology.:133562. doi:10.1016/j.ijcard.2025.133562
17. DePaolo J, Zamirpour S, Abramowitz S, Biagetti G, Judy R, Beeche C, Duda J, Gee J, Witschey WR, Chirinos JA, Goel NJ, Desai N, Szeto WY, Guo D, Milewicz DM, Levin MG, Pirruccello JP, Damrauer SM. Predicting Thoracic Aortic Dissection in a Diverse Biobank Using a Polygenic Risk Score. JACC: Advances. 2025;4(5):101743. doi:10.1016/j.jacadv.2025.101743
18. DePaolo J, Smelser DT, Guo D, Abramowitz S, Sisti GM, Judy R, Desai N, Szeto WY, Levin MG, Mirshahi H, Salzler G, Ryer E, Elmore J, LeMaire SA, Carey DJ, Milewicz DM, Damrauer SM. Genome-First Approach to Rare and Common Variant Risk of Thoracic Aortic Aneurysm and Dissection. doi:10.1101/2025.05.18.25327858
19. Ratman D, Tshiaba P, Levin M, Sun J, Tunstall T, Maier R, Shah P, Rabinowitz M, Rader DJ, Kumar A, Im K. Polygenic risk scores improve CAD risk prediction in individuals at borderline and intermediate clinical risk. npj Cardiovascular Health. 2025;2(1):1-14. doi:10.1038/s44325-025-00049-7
20. Khodursky S, Mimouni N, Levin MG. Recent developments in population biobanks and the genetic architecture of complex disease. Human Molecular Genetics.:ddaf036. doi:10.1093/hmg/ddaf036
21. Lee DSM, Cardone KM, Zhang DY, Tsao NL, Abramowitz S, Sharma P, DePaolo JS, Conery M, Aragam KG, Biddinger K, Dilitikas O, Hoffman-Andrews L, Judy RL, Khan A, Kullo IJ, Puckelwartz MJ, Reza N, Satterfield BA, Singhal P, Arany Z, Cappola TP, Carruth ED, Day SM, Do R, Haggerty CM, Joseph J, McNally EM, Nadkarni G, Owens AT, Rader DJ, Ritchie MD, Sun YV, Voight BF, Levin MG, Damrauer SM. Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum. Nature Genetics.:1-10. doi:10.1038/s41588-025-02140-2.
22. Levin MG, Koyama S, Woerner J, Zhang DY, Rodriguez A, Nandi T, Truong B, Abramowitz SA, Gupta H, Kamineni H, Hornsby W, Li Z, Cohron T, Huffman JE, Ellinor P, Kim D, Liao KP, Madduri RK, Voight BF, Verma A, Damrauer SM, Natarajan P. Genome-Wide Assessment of Pleiotropy Across >1000 Traits from Global Biobanks. doi:10.1101/2025.04.18.25326074
23. Tsao NL, Abramowitz SA, Shakt GE, Judy R, Hilliard AT, Biobank PM, Damrauer SM, Assimes TL, Clarke SL, Tcheandjieu C, Levin M. Angiographic Burden of Coronary Atherosclerosis Contributes To Adverse ASCVD Outcomes Independent Of Traditional Risk Factors. doi:10.1101/2025.04.06.25325252
24. Coronado PER, Zhou J, Fan X, Zanetti D, Naftaly JA, Prabala P, Jaimes AMM, Farah EN, Kundu S, Deshpande SS, Evergreen I, Kho PF, Ma Q, Hilliard AT, Abramowitz S, Pyarajan S, Dochtermann D, Damrauer SM, Chang K-M, Levin MG, Winn VD, Paşca AM, Plomondon ME, Waldo SW, Tsao PS, Kundaje A, Chi NC, Clarke SL, Red-Horse K, Assimes TL. CXCL12 drives natural variation in coronary artery anatomy across diverse populations. Cell. 2025;0(0). doi:10.1016/j.cell.2025.02.005
25. Lim J, Vujkovic M, Levin MG, Lorenz K, Voight BF, Zhang DY, Dudek MF, Pahl MC, Pippin JA, Su C, Manduchi E, Wells AD, Grant SFA, Abramowitz S, Damrauer SM, Mukherjee S, Yang G, Kaplan DE, BioBank PM, Rader DJ. Trans-ancestry genome-wide association meta-analysis of gallstone disease. doi:10.1101/2025.03.16.25324077
26. Neylan CJ, Levin MG, Hartmann K, Beigel K, Khodursky S, DePaolo JS, Abramowitz S, Furth EE, Heuckeroth RO, Damrauer SM, Maguire LH. Genome-wide association meta-analysis identifies 126 novel loci for diverticular disease and implicates connective tissue and colonic motility. doi:10.1101/2025.03.27.25324777
27. Venkatesh R, Cherlin T, Wayne N, Kumar R, Guare L, Singamneni V, Irving B, Dudek S, Center RG, Biobank PM, Levin MG, Setia-Verma S, Guerraty MA. Genome-Wide Association Study of Coronary Microvascular Disease assessed by cardiac perfusion Positron Emission Tomography converges on NF-кB pathway. doi:10.1101/2025.03.20.25324357
28. Yuan S, Chen J, Geng J, Zhao SS, Yarmolinsky J, Arkema EV, Abramowitz S, Levin MG, Tsilidis KK, Burgess S, Damrauer SM, Larsson SC. GWAS identifies genetic loci, lifestyle factors and circulating biomarkers that are risk factors for sarcoidosis. Nature Communications. 2025;16(1):2481. doi:10.1038/s41467-025-57829-z
29. Abramowitz SA, Boulier K, Keat K, Cardone KM, Shivakumar M, DePaolo J, Judy R, Bermudez F, Mimouni N, Neylan C, Kim D, Rader DJ, Ritchie MD, Voight BF, Pasaniuc B, Levin MG, Damrauer SM, Penn Medicine BioBank. Evaluating Performance and Agreement of Coronary Heart Disease Polygenic Risk Scores. JAMA. 2025;333(1):60-70. doi:10.1001/jama.2024.23784.
30. Khodursky S, Yuan S, Spin JM, Tsao PS, Levin MG, Damrauer SM. Plasma proteome-wide Mendelian randomization reveals the association of extracellular matrix proteins with abdominal aortic aneurysm. JVS-Vascular Science. 2025;6:100290. doi:10.1016/j.jvssci.2025.100290.
2024
31. Angueira A, Abramowitz SA, Levin MG. Unfolding the Link Between Transthyretin Stability and Survival. JAMA Cardiology. doi:10.1001/jamacardio.2024.4112
32. Choe D, Burke M, Brandimarto JA, Marti-Pamies I, Yob J, Yang Y, Morley MP, Drivas TG, Day S, Levin M, Damrauer S, Wang X, Cappola TP. Sex-Specific Effects of MTSS1 Downregulation on Dilated Cardiomyopathy. Circulation. 2024;150(20):1648-1651. doi:10.1161/CIRCULATIONAHA.124.070418
33. Park J, Levin MG, Zhang D, Reza N, Mead JO, Carruth ED, Kelly MA, Winters A, Kripke CM, Judy RL, Damrauer SM, Owens AT, Bastarache L, Verma A, Kinnamon DD, Hershberger RE, Ritchie MD, Rader DJ. Bidirectional Risk Modulator and Modifier Variant of Dilated and Hypertrophic Cardiomyopathy in BAG3. JAMA Cardiology. doi:10.1001/jamacardio.2024.3547
34. Streiffer CD, Levin MG, Witschey WR, Anyanwu EC. Denoising diffusion model for increased performance of detecting structural heart disease. medRxiv: The Preprint Server for Health Sciences.:2024.11.21.24317662. doi:10.1101/2024.11.21.24317662
35. Walker V, Sanderson E, Levin MG, Damraurer SM, Feeney T, Davies NM. Reading and conducting instrumental variable studies: Guide, glossary, and checklist. BMJ. 2024;387:e078093. doi:10.1136/bmj-2023-078093
36. DePaolo J, Biagetti G, Judy R, Wang GJ, Kelly J, Iyengar A, Goel NJ, Desai N, Szeto WY, Bavaria JE, Levin MG, Damrauer SM. Polygenic Scoring for Detection of Ascending Thoracic Aortic Dilation. Circulation Genomic and Precision Medicine.:e004512. doi:10.1161/CIRCGEN.123.004512.
37. Roberson JL, Farzaneh C, Neylan CJ, Judy R, Walker V, Damrauer SM, Levin MG, Maguire LH, Regeneron Genetics Center, Penn Medicine BioBank. Genome-Wide Association Study Identifies Genes for Hair Growth and Patterning are Associated With Pilonidal Disease. Diseases of the Colon and Rectum. 2024;67(9):1149-1157. doi:10.1097/DCR.0000000000003308
38. Sharma P, Judy R, Yuan S, Gellatly C, Saxby KL, Bown MJ, Levin M, Damrauer SM. Lipoprotein (a) is associated with increased risk of Abdominal Aortic Aneurysm. doi:10.1101/2024.09.13.24313646.
39. Clarke SL, Huang RDL, Hilliard AT, Levin MG, Sharma D, Thomson B, Lynch J, Tsao PS, Gaziano JM, Assimes TL, the VA Million Veteran Program. Genetically predicted lipoprotein(a) associates with coronary artery plaque severity independent of low-density lipoprotein cholesterol. European Journal of Preventive Cardiology.:zwae271. doi:10.1093/eurjpc/zwae271
40. Moore A, Venkatesh R, Levin M, Damrauer SM, Reza N, Cappola T, Ritchie MD. Connecting intermediate phenotypes to disease using multi-omics in heart failure. doi:10.1101/2024.08.06.24311572
41. Zhang DY, Levin MG, Duda JT, Landry LG, Witschey WR, Damrauer SM, Ritchie MD, Rader DJ. Protein-truncating variant in APOL3 increases chronic kidney disease risk in epistasis with APOL1 risk alleles. JCI Insight. doi:10.1172/jci.insight.181238
42. Lu HS, Temel RE, Levin MG, Damrauer SM, Daugherty A. Research Advances in Abdominal Aortic Aneurysms: Triglyceride-Rich Lipoproteins as a Therapeutic Target. Arteriosclerosis, Thrombosis, and Vascular Biology. 2024;44(6):1171-1174. doi:10.1161/ATVBAHA.124.320146
43. Sharma P, Klarin D, Voight BF, Tsao PS, Levin MG, Damrauer SM. Evaluation of Plasma Biomarkers for Causal Association With Peripheral Artery Disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 2024;44(5):1114-1123. doi:10.1161/ATVBAHA.124.320674.
44. Fanaroff AC, Coratti S, Farraday D, Norton L, Rareshide C, Zhu J, Levin MG, Damrauer SM, Giri JS, Chokshi NP, Jackson BM, Patel MS. Gamification-augmented home-based exercise for peripheral artery disease: Rationale and design of the GAMEPAD Study. American Heart Journal. 2024;270:95-102. doi:10.1016/j.ahj.2024.02.003
45. Dib M, Levin MG, Zhao L, Diab A, Wang Z, Ebert C, Salman O, Azzo JD, Gan S, Zamani P, Cohen JB, Gill D, Burgess S, Zagkos L, Empel V van, Richards AM, Doughty R, Rietzschel ER, Kammerhoff K, Kvikstad E, Maranville J, Schafer P, Seiffert DA, Ramirez‐Valle F, Gordon DA, Chang C, Javaheri A, Mann DL, Cappola TP, Chirinos JA. Proteomic Associations of Adverse Outcomes in Human Heart Failure. Journal of the American Heart Association. 2024;0(0):e031154. doi:10.1161/JAHA.123.031154.
46. Enzan N, Miyazawa K, Koyama S, Kurosawa R, Ieki H, Yoshida H, Takechi F, Fukuyama M, Osako R, Tomizuka K. Genome-wide analysis of heart failure yields insights into disease heterogeneity and enables prognostic prediction in the Japanese population. medRxiv. Accessed December 3, 2024. https://www.medrxiv.org/content/10.1101/2024.11.14.24317249.abstract
47. Shakt G, Tsao NL, Levin MG, Walker V, Kember RL, Klarin D, Tsao P, Voight BF, Scali ST, Damrauer SM. Major Depressive Disorder Impacts Peripheral Artery Disease Risk Through Intermediary Risk Factors. Journal of the American Heart Association. 2024;0(0):e030233. doi:10.1161/JAHA.123.030233
2023
48. Levin MG, Burgess S. Mendelian Randomization as a Tool for Cardiovascular Research: A Review. JAMA Cardiology. doi:10.1001/jamacardio.2023.4115
49. Kim B, Zhao W, Tang SY, Levin MG, Ibrahim A, Yang Y, Roberts EM, Lai L, Li J, Assoian RK, FitzGerald GA, Arany Z. Endothelial lipid droplets suppress eNOS to link high fat consumption to blood pressure elevation. The Journal of Clinical Investigation. doi:10.1172/JCI173160
50. Roychowdhury T, Klarin D, Levin MG, Spin JM, Rhee YH, Deng A, Headley CA, Tsao NL, Gellatly C, Zuber V, Shen F, Hornsby WE, Laursen IH, Verma SS, Locke AE, Einarsson G, Thorleifsson G, Graham SE, Dikilitas O, Pattee JW, Judy RL, Pauls-Verges F, Nielsen JB, Wolford BN, Brumpton BM, Dilmé J, Peypoch O, Juscafresa LC, Edwards TL, Li D, Banasik K, Brunak S, Jacobsen RL, Garcia-Barrio MT, Zhang J, Rasmussen LM, Lee R, Handa A, Wanhainen A, Mani K, Lindholt JS, Obel LM, Strauss E, Oszkinis G, Nelson CP, Saxby KL, Herwaarden JA van, Laan SW van der, Setten J van, Camacho M, Davis FM, Wasikowski R, Tsoi LC, Gudjonsson JE, Eliason JL, Coleman DM, Henke PK, Ganesh SK, Chen YE, Guan W, Pankow JS, Pankratz N, Pedersen OB, Erikstrup C, Tang W, Hveem K, Gudbjartsson D, Gretarsdottir S, Thorsteinsdottir U, Holm H, Stefansson K, Ferreira MA, Baras A, Kullo IJ, Ritchie MD, Christensen AH, Iversen KK, Eldrup N, Sillesen H, Ostrowski SR, Bundgaard H, Ullum H, Burgess S, Gill D, Gallagher K, Sabater-Lleal M, Surakka I, Jones GT, Bown MJ, Tsao PS, Willer CJ, Damrauer SM. Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target. Nature Genetics.:1-12. doi:10.1038/s41588-023-01510-y.
51. Levin MG, Aragam KG. Truncations of Titin and Left Atrial Cardiomyopathy: Comment on Henkens et al.’s article, Left Atrial Function in Patients With Titin Cardiomyopathy. Journal of Cardiac Failure. doi:10.1016/j.cardfail.2023.06.019
52. Zuber V, Lewin A, Levin MG, Haglund A, Ben-Aicha S, Emanueli C, Damrauer S, Burgess S, Gill D, Bottolo L. Multi-response Mendelian randomization: Identification of shared and distinct exposures for multimorbidity and multiple related disease outcomes. American Journal of Human Genetics. 2023;110(7):1177-1199. doi:10.1016/j.ajhg.2023.06.005
53. Klarin D, Devineni P, Sendamarai AK, Angueira AR, Graham SE, Shen YH, Levin MG, Pirruccello JP, Surakka I, Karnam PR, Roychowdhury T, Li Y, Wang M, Aragam KG, Paruchuri K, Zuber V, Shakt GE, Tsao NL, Judy RL, Vy HMT, Verma SS, Rader DJ, Do R, Bavaria JE, Nadkarni GN, Ritchie MD, Burgess S, Guo D, Ellinor PT, LeMaire SA, Milewicz DM, Willer CJ, Natarajan P, Tsao PS, Pyarajan S, Damrauer SM. Genome-wide association study of thoracic aortic aneurysm and dissection in the Million Veteran Program. Nature Genetics.:1-10. doi:10.1038/s41588-023-01420-z
54. Levin MG, Rader DJ. Polygenic risk scores for dyslipidemia and atherosclerotic cardiovascular disease: Progress toward clinical implementation. Best Practice & Research Clinical Endocrinology & Metabolism. 2023;37(3):101702. doi:10.1016/j.beem.2022.101702
55. Tsao NL, Judy R, Levin MG, Shakt G, Center RG, BioBank PM, Voight BF, Chen J, Damrauer SM. Evaluation of the Performance of the RECODe Equation with the Addition of Polygenic Risk Scores for Adverse Cardiovascular Outcomes in Individuals with Type II Diabetes. doi:10.1101/2023.05.03.23289457
56. Yuan S, Levin MG, Titova OE, Chen J, Sun Y, Million Veteran Program VA, Åkesson A, Li X, Damrauer SM, Larsson SC. Sleep duration, daytime napping, and risk of peripheral artery disease: Multinational cohort and Mendelian randomization studies. European Heart Journal Open. 2023;3(2):oead008. doi:10.1093/ehjopen/oead008.
57. Lee DSM, Damrauer SM, Levin MG. Genetics of atrial fibrillation. Current Opinion in Cardiology. doi:10.1097/HCO.0000000000001031
58. Stankov S, Center RG, Vitali C, Park J, Nguyen D, Mayne L, Englander SW, Levin MG, Vujkovic M, Hand NJ, Phillips MC, Rader DJ. Comparison of the structure-function properties of wild-type human apoA-V and a C-terminal truncation associated with elevated plasma triglycerides. doi:10.1101/2023.02.21.23286268
59. DePaolo J, Levin MG, Tcheandjieu C, Priest J, Gill D, Burgess S, Damrauer SM, Chirinos JA. Relationship Between Ascending Thoracic Aortic Diameter and Blood Pressure: A Mendelian Randomization Study. Arteriosclerosis, Thrombosis, and Vascular Biology. 2023;0(0). doi:10.1161/ATVBAHA.122.318149
60. Levin MG, Huffman JE, Verma A, Sullivan KA, Rodriguez AA, Kainer D, Garvin MR, Lane M, Cashman M, Miller JI, Won H, Li B, Luo Y, Jarvik GP, Hakonarson H, Jasper EA, Bick AG, Tsao PS, Ritchie MD, Jacobson DA, Madduri RK, Damrauer SM. Genetics of varicose veins reveals polygenic architecture and genetic overlap with arterial and venous disease. Nature Cardiovascular Research.:1-14. doi:10.1038/s44161-022-00196-5
61. Levin MG, Damrauer SM. Lipoprotein(a) and progression of aortic valve calcification: A case of collider bias? European Heart Journal.:ehac638. doi:10.1093/eurheartj/ehac638
62. Huang B, DePaolo J, Judy RL, Shakt G, Witschey WR, Levin MG, Gershuni VM. Relationships between body fat distribution and metabolic syndrome traits and outcomes: A mendelian randomization study. PloS One. 2023;18(10):e0293017. doi:10.1371/journal.pone.0293017
63. Reza N, Levin MG, Vidula MK, Bravo PE, Damrauer SM, Ritchie MD, null null, Chahal CAA, Owens AT. Prevalence of Pathogenic Variants in Dilated Cardiomyopathy–Associated Genes in Patients Evaluated for Cardiac Sarcoidosis. Circulation: Genomic and Precision Medicine. 2023;0(0):e003850. doi:10.1161/CIRCGEN.122.003850.
64. Zhao G, Ma Y, Hasler JS, Damrauer S, Levin M, Chen J. A Nested Semiparametric Method for Case-Control Study with Missingness. Scandinavian Journal of Statistics. 2023;n/a(n/a). doi:10.1111/sjos.12673
65. Katz AE, Yang M-L, Levin MG, Tcheandjieu C, Mathis M, Hunker K, Blackburn S, Eliason JL, Coleman DM, Fendrikova-Mahlay N, Gornik HL, Karmakar M, Hill H, Xu C, Zawistowski M, Brummett CM, Zoellner S, Zhou X, O’Donnell C, Douglas JA, Assimes TL, Tsao PS, Li JZ, Damrauer SM, Stanley JC, Ganesh SK, VA Million Veteran Program. Fibromuscular Dysplasia and Abdominal Aortic Aneurysms Are Dimorphic Sex-Specific Diseases With Shared Complex Genetic Architecture. Circulation Genomic and Precision Medicine.:e003496. doi:10.1161/CIRCGEN.121.003496.
2022
66. Levin MG, Tsao NL, Singhal P, Liu C, Vy HMT, Paranjpe I, Backman JD, Bellomo TR, Bone WP, Biddinger KJ, Hui Q, Dikilitas O, Satterfield BA, Yang Y, Morley MP, Bradford Y, Burke M, Reza N, Charest B, Judy RL, Puckelwartz MJ, Hakonarson H, Khan A, Kottyan LC, Kullo I, Luo Y, McNally EM, Rasmussen-Torvik LJ, Day SM, Do R, Phillips LS, Ellinor PT, Nadkarni GN, Ritchie MD, Arany Z, Cappola TP, Margulies KB, Aragam KG, Haggerty CM, Joseph J, Sun YV, Voight BF, Damrauer SM. Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure. Nature Communications. 2022;13(1):6914. doi:10.1038/s41467-022-34216-6
67. Murashige D, Jung JW, Neinast MD, Levin MG, Chu Q, Lambert JP, Garbincius JF, Kim B, Hoshino A, Marti-Pamies I, McDaid KS, Shewale SV, Flam E, Yang S, Roberts E, Li L, Morley MP, Bedi KC, Hyman MC, Frankel DS, Margulies KB, Assoian RK, Elrod JW, Jang C, Rabinowitz JD, Arany Z. Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure. Cell Metabolism. 2022;34(11):1749-1764.e7. doi:10.1016/j.cmet.2022.09.008
68. Thibord F, Klarin D, Brody JA, Chen M-H, Levin MG, Chasman DI, Goode EL, Hveem K, Teder-Laving M, Martinez-Perez A, Aïssi D, Daian-Bacq D, Ito K, Natarajan P, Lutsey PL, Nadkarni GN, Vries PS de, Cuellar-Partida G, Wolford BN, Pattee JW, Kooperberg C, Braekkan SK, Li-Gao R, Saut N, Sept C, Germain M, Judy RL, Wiggins KL, Ko D, O’Donnell CJ, Taylor KD, Giulianini F, De Andrade M, Nøst TH, Boland A, Empana J-P, Koyama S, Gilliland T, Do R, Huffman JE, Wang X, Zhou W, Manuel Soria J, Carlos Souto J, Pankratz N, Haessler J, Hindberg K, Rosendaal FR, Turman C, Olaso R, Kember RL, Bartz TM, Lynch JA, Heckbert SR, Armasu SM, Brumpton B, Smadja DM, Jouven X, Komuro I, Clapham KR, Loos RJF, Willer CJ, Sabater-Lleal M, Pankow JS, Reiner AP, Morelli VM, Ridker PM, Vlieg A van H, Deleuze J-F, Kraft P, Rader DJ, Global Biobank Meta-Analysis Initiative; Estonian Biobank Research Team; 23andMe Research Team; Biobank Japan; CHARGE Hemostasis Working Group, Min Lee K, Psaty BM, Heidi Skogholt A, Emmerich J, Suchon P, Rich SS, Vy HMT, Tang W, Jackson RD, Hansen J-B, Morange P-E, Kabrhel C, Trégouët D-A, Damrauer SM, Johnson AD, Smith NL. Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors. Circulation. 2022;146(16):1225-1242. doi:10.1161/CIRCULATIONAHA.122.059675
69. Tcheandjieu C, Zhu X, Hilliard AT, Clarke SL, Napolioni V, Ma S, Lee KM, Fang H, Chen F, Lu Y, Tsao NL, Raghavan S, Koyama S, Gorman BR, Vujkovic M, Klarin D, Levin MG, Sinnott-Armstrong N, Wojcik GL, Plomondon ME, Maddox TM, Waldo SW, Bick AG, Pyarajan S, Huang J, Song R, Ho Y-L, Buyske S, Kooperberg C, Haessler J, Loos RJF, Do R, Verbanck M, Chaudhary K, North KE, Avery CL, Graff M, Haiman CA, Le Marchand L, Wilkens LR, Bis JC, Leonard H, Shen B, Lange LA, Giri A, Dikilitas O, Kullo IJ, Stanaway IB, Jarvik GP, Gordon AS, Hebbring S, Namjou B, Kaufman KM, Ito K, Ishigaki K, Kamatani Y, Verma SS, Ritchie MD, Kember RL, Baras A, Lotta LA, Kathiresan S, Hauser ER, Miller DR, Lee JS, Saleheen D, Reaven PD, Cho K, Gaziano JM, Natarajan P, Huffman JE, Voight BF, Rader DJ, Chang K-M, Lynch JA, Damrauer SM, Wilson PWF, Tang H, Sun YV, Tsao PS, O’Donnell CJ, Assimes TL. Large-scale genome-wide association study of coronary artery disease in genetically diverse populations. Nature Medicine.:1-13. doi:10.1038/s41591-022-01891-3
70. Chen BY, Bone WP, Lorenz K, Levin M, Ritchie MD, Voight BF. ColocQuiaL: A QTL-GWAS colocalization pipeline. Bioinformatics (Oxford, England).:btac512. doi:10.1093/bioinformatics/btac512
71. Levin MG, Nakao T, Zekavat SM, Koyama S, Bick AG, Niroula A, Ebert B, Damrauer SM, Natarajan P. Genetics of smoking and risk of clonal hematopoiesis. Scientific Reports. 2022;12(1):7248. doi:10.1038/s41598-022-09604-z
72. Walker VM, Vujkovic M, Carter AR, Davies NM, Udler MS, Levin MG, Davey Smith G, Voight BF, Gaunt TR, Damrauer SM. Separating the direct effects of traits on atherosclerotic cardiovascular disease from those mediated by type 2 diabetes. Diabetologia. 2022;65(5):790-799. doi:10.1007/s00125-022-05653-1
73. Verma A, Tsao NL, Thomann LO, Ho Y-L, Iyengar SK, Luoh S-W, Carr R, Crawford DC, Efird JT, Huffman JE, Hung A, Ivey KL, Levin MG, Lynch J, Natarajan P, Pyarajan S, Bick AG, Costa L, Genovese G, Hauger R, Madduri R, Pathak GA, Polimanti R, Voight B, Vujkovic M, Zekavat SM, Zhao H, Ritchie MD, Initiative VMVPCS, Chang K-M, Cho K, Casas JP, Tsao PS, Gaziano JM, O’Donnell C, Damrauer SM, Liao KP. A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program. PLOS Genetics. 2022;18(4):e1010113. doi:10.1371/journal.pgen.1010113
2021
74. Levin MG, Klarin D, Georgakis MK, Lynch J, Liao KP, Voight BF, O’Donnell CJ, Chang K-M, Assimes TL, Tsao PS, Damrauer SM, VA Million Veteran Program. A Missense Variant in the IL-6 Receptor and Protection From Peripheral Artery Disease. Circulation Research. 2021;129(10):968-970. doi:10.1161/CIRCRESAHA.121.319589
75. Khetarpal SA, Vitali C, Levin MG, Klarin D, Park J, Pampana A, Millar JS, Kuwano T, Sugasini D, Subbaiah PV, Billheimer JT, Natarajan P, Rader DJ. Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins. PLoS genetics. 2021;17(9):e1009802. doi:10.1371/journal.pgen.1009802
76. Levin MG. Circulating Lipids and COVID-19: Insights From Mendelian Randomization. Arteriosclerosis, Thrombosis, and Vascular Biology.:ATVBAHA.121.316940. doi:10.1161/ATVBAHA.121.316940
77. Park J, Packard EA, Levin MG, Judy RL, Regeneron Genetics Center, Damrauer SM, Day SM, Ritchie MD, Rader DJ. A genome-first approach to rare variants in hypertrophic cardiomyopathy genes MYBPC3 and MYH7 in a medical biobank. Human Molecular Genetics.:ddab249. doi:10.1093/hmg/ddab249
78. Levin MG, Zuber V, Walker VM, Klarin D, Lynch J, Malik R, Aday AW, Bottolo L, Pradhan AD, Dichgans M, Chang K-M, Rader DJ, Tsao PS, Voight BF, Gill D, Burgess S, Damrauer SM. Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease. Circulation. 2021;144(5):353-364. doi:10.1161/CIRCULATIONAHA.121.053797.
79. Levin MG. Remnant Lipoproteins as a Target for Atherosclerosis Risk Reduction. Arteriosclerosis, Thrombosis, and Vascular Biology. 2021;41(6):2076-2079. doi:10.1161/ATVBAHA.121.316341
80. Levin MG, Klarin D, Walker VM, Gill D, Lynch J, Hellwege JN, Keaton JM, Lee KM, Assimes TL, Natarajan P, Hung AM, Edwards TL, Rader DJ, Gaziano JM, Davies NM, Tsao PS, Chang K-M, Voight BF, Damrauer SM, VA Million Veteran Program. Association Between Genetic Variation in Blood Pressure and Increased Lifetime Risk of Peripheral Artery Disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 2021;41(6):2027-2034. doi:10.1161/ATVBAHA.120.315482
81. Gill D, Zuber V, Dawson J, Pearson-Stuttard J, Carter AR, Sanderson E, Karhunen V, Levin MG, Wootton RE, Klarin D, Tsao PS, Tsilidis KK, Damrauer SM, Burgess S, Elliott P. Risk factors mediating the effect of body mass index and waist-to-hip ratio on cardiovascular outcomes: Mendelian randomization analysis. International Journal of Obesity.:1-11. doi:10.1038/s41366-021-00807-4
82. Georgakis MK, Malik R, Li X, Gill D, Levin MG, Vy HMT, Judy R, Ritchie M, Verma SS, Regeneron Genetics Center, Nadkarni GN, Damrauer SM, Theodoratou E, Dichgans M. Genetically Downregulated Interleukin-6 Signaling Is Associated With a Favorable Cardiometabolic Profile: A Phenome-Wide Association Study. Circulation. 2021;143(11):1177-1180. doi:10.1161/CIRCULATIONAHA.120.052604
83. Hyman MC, Levin MG, Gill D, Walker VM, Georgakis MK, Davies NM, Marchlinski FE, Damrauer SM. Genetically Predicted Blood Pressure and Risk of Atrial Fibrillation. Hypertension. doi:10.1161/hypertensionaha.120.16191.
84. Levin MG, Klarin D, Assimes TL, Freiberg MS, Ingelsson E, Lynch J, Natarajan P, O’Donnell C, Rader DJ, Tsao PS, Chang K-M, Voight BF, Damrauer SM, VA Million Veteran Program. Genetics of Smoking and Risk of Atherosclerotic Cardiovascular Diseases: A Mendelian Randomization Study. JAMA Network Open. 2021;4(1):e2034461. doi:10.1001/jamanetworkopen.2020.34461
85. Bellomo TR, Bone WP, Chen BY, Gawronski KAB, Zhang D, Park J, Levin M, Tsao N, Klarin D, Lynch J, Assimes TL, Gaziano JM, Wilson PW, Cho K, Vujkovic M, O’Donnell CJ, Chang K-M, Tsao PS, Rader DJ, Ritchie MD, Damrauer SM, Voight BF. Multi-Trait Genome-Wide Association Study of Atherosclerosis Detects Novel Pleiotropic Loci. Frontiers in Genetics. 2021;12:787545. doi:10.3389/fgene.2021.787545
2020
86. Markman TM, Plappert T, De Feria Alsina A, Levin MG, Amankwah N, Sheth S, Gertz ZM, Schaller RD, Marchlinski FE, Rame JE, Frankel DS. Improvement in tricuspid regurgitation following catheter ablation of atrial fibrillation. Journal of Cardiovascular Electrophysiology. 2020;31(11):2883-2888. doi:10.1111/jce.14707
87. Thom CS, Ding Z, Levin MG, Damrauer SM, Lee KM, Lynch J, Chang K-M, Tsao PS, Cho K, Wilson PWF, Assimes TL, Sun YV, O’Donnell CJ, VA Million Veteran Program, Vujkovic M, Voight BF. Genetic determinants of increased body mass index mediate the effect of smoking on increased risk for type 2 diabetes but not coronary artery disease. Human Molecular Genetics. 2020;29(19):3327-3337. doi:10.1093/hmg/ddaa193
88. Klarin D, Verma SS, Judy R, Dikilitas O, Wolford BN, Paranjpe I, Levin MG, Pan C, Tcheandjieu C, Spin JM, Lynch J, Assimes TL, Åldstedt Nyrønning L, Mattsson E, Edwards TL, Denny J, Larson E, Lee MTM, Carrell D, Zhang Y, Jarvik GP, Gharavi AG, Harley J, Mentch F, Pacheco JA, Hakonarson H, Skogholt AH, Thomas L, Gabrielsen ME, Hveem K, Nielsen JB, Zhou W, Fritsche L, Huang J, Natarajan P, Sun YV, DuVall SL, Rader DJ, Cho K, Chang K-M, Wilson PWF, O’Donnell CJ, Kathiresan S, Scali ST, Berceli SA, Willer C, Jones GT, Bown MJ, Nadkarni G, Kullo IJ, Ritchie M, Damrauer SM, Tsao PS, Veterans Affairs Million Veteran Program†. Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program. Circulation. 2020;142(17):1633-1646. doi:10.1161/CIRCULATIONAHA.120.047544
89. Levin MG, Judy R, Gill D, Vujkovic M, Verma SS, Bradford Y, Regeneron Genetics Center, Ritchie MD, Hyman MC, Nazarian S, Rader DJ, Voight BF, Damrauer SM. Genetics of height and risk of atrial fibrillation: A Mendelian randomization study. PLoS medicine. 2020;17(10):e1003288. doi:10.1371/journal.pmed.1003288
91. Kember RL, Levin MG, Cousminer DL, Tsao N, Judy R, Schur GM, Lubitz SA, Ellinor PT, Mccormack SE, Grant SFA, Rader DJ, Voight BF, Damrauer SM. Genetically Determined Birthweight Associates with Atrial Fibrillation: A Mendelian Randomization Study. Circulation: Genomic and Precision Medicine. doi:10.1161/circgen.119.002553.
92. Levin MG, Rader DJ. Polygenic Risk Scores and Coronary Artery Disease. Circulation.:637-640. doi:10.1161/CIRCULATIONAHA.119.044770
93. Park J, Levin MG, Haggerty CM, Hartzel DN, Judy R, Kember RL, Reza N, Ritchie MD, Owens AT, Damrauer SM, Rader DJ. A genome-first approach to aggregating rare genetic variants in LMNA for association with electronic health record phenotypes. Genetics in Medicine. 2020;22(1):102-111. doi:10.1038/s41436-019-0625-8
94. Tabet F, Lee S, Zhu W, Levin MG, Toth CL, Cuesta Torres LF, Vinh A, Kim HA, Chu HX, Evans MA, Kuzmich ME, Drummond GR, Remaley AT, Rye KA, Sobey CG, Vickers KC. microRNA-367-3p regulation of GPRC5A is suppressed in ischemic stroke. Journal of Cerebral Blood Flow and Metabolism. 2020;40(6):1300-1315. doi:10.1177/0271678x19858637
2019
95. Damrauer SM, Chaudhary K, Cho JH, Liang LW, Argulian E, Chan L, Dobbyn A, Guerraty MA, Judy R, Kay J, Kember RL, Levin MG, Saha A, Van Vleck T, Verma SS, Weaver J, Abul-Husn NS, Baras A, Chirinos JA, Drachman B, Kenny EE, Loos RJF, Narula J, Overton J, Reid J, Ritchie M, Sirugo G, Nadkarni G, Rader DJ, Do R. Association of the V122I Hereditary Transthyretin Amyloidosis Genetic Variant With Heart Failure Among Individuals of African or Hispanic/Latino Ancestry. JAMA. 2019;322(22):2191-2202. doi:10.1001/jama.2019.17935
96. Klarin D, Busenkell E, Judy R, Lynch J, Levin MG, Haessler J, Aragam K, Chaffin M, Haas M, Lindström S, Assimes TL, Huang J, Min Lee K, Shao Q, Huffman JE, Kabrhel C, Huang Y, Sun YV, Vujkovic M, Saleheen D, Miller DR, Reaven P, DuVall S, Boden WE, Pyarajan S, Reiner AP, Trégouët DA, Henke P, Kooperberg C, Gaziano JM, Concato J, Rader DJ, Cho K, Chang KM, Wilson PWF, Smith NL, O’Donnell CJ, Tsao PS, Kathiresan S, Obi A, Damrauer SM, Natarajan P. Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease. Nature Genetics. 2019;51(11):1574-1579. doi:10.1038/s41588-019-0519-3
97. Hoshino A, Wang W jia, Wada S, McDermott-Roe C, Evans CS, Gosis B, Morley MP, Rathi KS, Li J, Li K, Yang S, McManus MJ, Bowman C, Potluri P, Levin MG, Damrauer S, Wallace DC, Holzbaur ELF, Arany Z. The ADP/ATP translocase drives mitophagy independent of nucleotide exchange. Nature. 2019;575(7782):375-379. doi:10.1038/s41586-019-1667-4
98. Bick AG, Akwo E, Robinson-Cohen C, Lee K, Lynch J, Assimes TL, Duvall S, Edwards T, Fang H, Freiberg SM, Giri A, Huffman JE, Huang J, Hull L, Kember RL, Klarin D, Lee JS, Levin MG, Miller DR, Natarajan P, Saleheen D, Shao Q, Sun YV, Tang H, Wilson O, Chang KM, Cho K, Concato J, Gaziano JM, Kathiresan S, O’Donnell CJ, Rader DJ, Tsao PS, Wilson PW, Hung AM, Damrauer SM. Association of APOL1 Risk Alleles with Cardiovascular Disease in Blacks in the Million Veteran Program. Circulation. 2019;140(12):1031-1040. doi:10.1161/circulationaha.118.036589
99. Haggerty CM, Damrauer SM, Levin MG, Birtwell D, Carey DJ, Golden AM, Hartzel DN, Hu Y, Judy R, Kelly MA, Kember RL, Lester Kirchner H, Leader JB, Liang L, Mcdermott-Roe C, Babu A, Morley M, Nealy Z, Person TN, Pulenthiran A, Small A, Smelser DT, Stahl RC, Sturm AC, Williams H, Baras A, Margulies KB, Cappola TP, Dewey FE, Verma A, Zhang X, Correa A, Hall ME, Wilson JG, Ritchie MD, Rader DJ, Murray MF, Fornwalt BK, Arany Z. Genomics-First Evaluation of Heart Disease Associated With Titin-Truncating Variants. Circulation. 2019;140(1):42-54. doi:10.1161/circulationaha.119.039573
2018
100. Levin MG, Kember RL, Judy R, Birtwell D, Williams H, Arany Z, Giri J, Guerraty M, Cappola T, Chen J, Rader DJ, Damrauer SM. Genomic Risk Stratification Predicts All-Cause Mortality After Cardiac Catheterization. Circulation Genomic and precision medicine. 2018;11(11):e002352. doi:10.1161/circgen.118.002352
2016
101. Levin MG, Cennimo D, Chen S, Lamba S. Teaching Clinical Reasoning to Medical Students: A Case-Based Illness Script Worksheet Approach. MedEdPORTAL. 2016;12(1). doi:10.15766/mep_2374-8265.10445
2015
102. Wang Y, McNutt MC, Banfi S, Levin MG, Holland WL, Gusarova V, Gromada J, Cohen JC, Hobbs HH. Hepatic ANGPTL3 regulates adipose tissue energy homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 2015;112(37):11630-11635. doi:10.1073/pnas.1515374112
2014
103. Vickers KC, Landstreet SR, Levin MG, Shoucri BM, Toth CL, Taylor RC, Palmisano BT, Tabet F, Cui HL, Rye KA, Sethupathy P, Remaley AT. MicroRNA-223 coordinates cholesterol homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 2014;111(40):14518-14523. doi:10.1073/pnas.1215767111
104. Tabet F, Vickers KC, Cuesta Torres LF, Wiese CB, Shoucri BM, Lambert G, Catherinet C, Prado-Lourenco L, Levin MG, Thacker S, Sethupathy P, Barter PJ, Remaley AT, Rye KA. HDL-transferred microRNA-223 regulates ICAM-1 expression in endothelial cells. Nature Communications. 2014;5:3292. doi:10.1038/ncomms4292
2013
105. Feng Q, Vickers KC, Anderson MP, Levin MG, Chen W, Harrison DG, Wilke RA. A common functional promoter variant links CNR1 gene expression to HDL cholesterol level. Nature Communications. 2013;4. doi:10.1038/ncomms2973
106. Toh SA, Levin MG, Rader DJ. Atherogenic lipid metabolism in obesity. In: Metabolic Basis of Obesity. Springer New York; 2011:293-309. doi:10.1007/978-1-4419-1607-5_15
2010
107. Burkhardt R, Toh SA, Lagor WR, Birkeland A, Levin MG, Li X, Robblee M, Fedorov VD, Yamamoto M, Satoh T, Akira S, Kathiresan S, Breslow JL, Rader DJ. Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice. Journal of Clinical Investigation. 2010;120(12):4410-4414. doi:10.1172/jci44213